In Teenage Mutant Ninja Turtles: The Hyperstone Heist, the game is designed to reward an extra life starting with 100 kills, then at 300 kill, etc. such that one way of sustaining your life is to quickly dispatch any incoming mobs. Fortunately, compared to Turtles in Time, The Hyperstone Heist game allows more control over what moves are performed and when. One trick is to get close to enemies and quickly tap the attack button resulting in one of the enemies being caught and then thrown from side to side. While the enemy is thrown from side to side any damage to other enemies caught in the whirlwind is instantly fatal such that larger groups of mobs can be killed with just one single move. The main tactic leveraging this particularity of The Hyperstone Heist would be to attempt and rack up as many kills as possible in order to increase the amount of lives. The game becomes fairly easily completable with one single continue.

On the second level, it is sufficient to stay in the top upper left side of the screen in order to evade the enemies that jump around.